Scientific Objectives

MULTIPLE SCLEROSIS

General Multiple Sclerosis

The following area of research is currently being considered with a focus on Multiple Sclerosis (MS)

  • MS and its treatment in special populations, i.e. geriatric or pediatric patients, family planning, LGBTQ+ patients, underrepresented populations

Research support is awarded on a highly competitive basis, and submission of research proposals in this area of interest does not guarantee support will be awarded.

MS Therapies

Biogen MS therapies include the following products.

  • Disease Modifying Therapies
    Dimethyl fumarate
    Diroximel fumarate
    Natalizumab
    SC and IM Peginterferon beta-1a
    IM Interferon beta-1a
  • Symptomatic Therapies
    Prolonged-release fampridine (ex-USA)


The following areas of research are currently being considered with a focus on

Dimethyl Fumarate:

  • Studies deciphering the neuroprotective potential of dimethyl fumarate 
  • Studies deciphering how dimethyl fumarate may cause lymphopenia

Diroximel Fumarate:

  • Comparative effectiveness as assessed by PROs, quality of life, workability, treatment satisfaction and/or adherence vs newer DMTs in the treatment of naïve and/or switch patients
  • Studies deciphering how diroximel fumarate may cause lymphopenia

Natalizumab 

  • Examination of long-term outcomes

Peginterferon beta-1a and Interferon beta-1a:

  • Real world effectiveness, safety and tolerability vs. other platform MS therapies

General MS Therapies:

  • Real world comparative effectiveness, switching and sequencing strategies, and adherence to therapies.

Out of scope:

  • Biomarker studies to identify specific responder populations among patients treated with MS therapies
  • Studies on MS therapy MoA

Research support is awarded on a highly competitive basis, and submission of research proposals in these areas of interest does not guarantee support will be awarded.

Neuromuscular

SMA

Funding for studies related to Spinal Muscular Atrophy has been fulfilled for 2023. Areas of research for 2024 will be posted later.

 

 

 

Submit your research proposal or manage your study today

If you have any questions or would like to get in touch with the Biogen local medical contact in your country/region, please email us at MedicalResearch@biogen.com.